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| Type |
Poster Presentation |
| Area |
Organic Chemistry |
| Room No. |
Event Hall |
| Time |
4월 19일 (목요일) 11:00~12:30 |
| Code |
ORGN.P-515 |
| Subject |
Calixarne Based Oligo Ethylene Glycol Modified Catalyst for Nucleophilic Fluorination |
| Authors |
SEOKMIN KANG, Dong Wook Kim*, Chul Hee Kim, Suah Yoo
Department of Chemistry, Inha University, Korea
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| Abstract |
Nucleophilic fluorination reaction is very important in PET(Positron Emission Tomography) and Medicinal Chemistry. Because F-18 has relatively short half life, it have to be introduced to biomolecules in short time. So in last few decades, many methodologies for fast F-18 radio fluorination have been studies. In our study, we synthesized calix[4]arene based (PTC) phase transfer type promoter for fluorination. There are two moiety; one is crown ether, the other is polyethylene glycol. They have been also known as PTC in previous studies. So we combined them in one molecule expecting they can exhibit synergetic effect for PTC. We expect this promoter for fluorination can be used as efficient promoter for production of PET probes. |
| E-mail |
james1231@naver.com |
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121st General Meeting of the KCS