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|
| Type |
Poster Presentation |
| Area |
Electrochemistry |
| Room No. |
Event Hall |
| Time |
4월 20일 (금요일) 11:00~12:30 |
| Code |
ELEC.P-641 |
| Subject |
Conducting Polymer Nanotube Transistor Based Dopamine Aptasensor
|
| Authors |
Jiyeon Lee, oh seok kwon1,*
Kyung Hee University, Korea
1BNT research center, KRIBB, Korea
|
| Abstract |
In this study, ultrasensitive and precise detection of a representative brain hormone, dopamine was pursued and demonstrated using functional conducting polymer nanotubes modified with aptamer. The produced aptasensor was composed of a micropatterned gold electrode, carboxylated polypyrrole nanotubes, and specific aptamer molecules. The sensor was constructed by sequential deposition of the PPy-COOH nanotubes and aptamer molecules on the electrode. The sensitivity and selectivity of this sensor were monitored using field effect transistor type measurements. In addition, real dopamine released from PC12 and SH-SY5Y cells induced by high concentration potassium ion (K+) stimulus were also analyzed and compared with the data obtained from the sensitivity (1 nM) and selectivity tests. This article can provide the feasibility for practical use of simple and efficient field effect transistor type aptasensor |
| E-mail |
vito9270@kribb.re.kr |
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121st General Meeting of the KCS