121st General Meeting of the KCS

Type Poster Presentation
Area Medicinal Chemistry
Room No. Event Hall
Time 4월 19일 (목요일) 11:00~12:30
Code MEDI.P-661
Subject Mini-Review of corrole potentials as biological effector molecules
Authors sungrae kim, Yonghwang Ha1,*
Jungwon University, Korea
1Department of Medical Bioscience, Jungwon University, Korea
Abstract Recently corrole compounds, which have very similar core structure with porphyrin, have been attracted many interests with respect to synthetic strategies and biological applications. Although photophysical properties of corroles are similar porphyrin molecules, biological characteristics exhibit more improved applicability for molecular imaging, detection and degradation of tumors, G-quadraplex regulators, catalytic degradation of reactive oxygen/nitrogen species (ROS/RNS), anti-microorganism and generation of singlet oxygen as photosensitizers. Herein, we reviewed various free base- and metallo-corroles and their biological applications.
E-mail hyh3455@jwu.ac.kr