|
Type |
Poster Presentation |
Area |
Medicinal Chemistry |
Room No. |
Event Hall |
Time |
4월 19일 (목요일) 11:00~12:30 |
Code |
MEDI.P-663 |
Subject |
Identification of HTR2 antagonists for metabolic disease |
Authors |
Minhee Kim, HAUSHABHAU PAGIRE, SUVARNA HAUSHABHAU PAGIRE, JIN HEE AHN* Department of Chemistry, Gwangju Institute of Science and Technology, Korea |
Abstract |
Obesity rate is rapidly increasing every year in highly populated countries. Currently, only five drugs are available for obesity, but they have low efficacy and safety issues. This represents high medical unmet needs for a new drug which has higher efficacy and lower adverse effect than prevailing drugs. HTR2a is significantly associated with obesity. Lipogenesis in mature adipocytes was regulated through HTR2. In this poster presentation, discovery and biological evaluation of HTR2 antagonist will be presented |
E-mail |
kmh0724@gist.ac.kr |
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