121st General Meeting of the KCS

Type Poster Presentation
Area Medicinal Chemistry
Room No. Event Hall
Time 4월 19일 (목요일) 11:00~12:30
Code MEDI.P-663
Subject Identification of HTR2 antagonists for metabolic disease
Authors Minhee Kim, HAUSHABHAU PAGIRE, SUVARNA HAUSHABHAU PAGIRE, JIN HEE AHN*
Department of Chemistry, Gwangju Institute of Science and Technology, Korea
Abstract Obesity rate is rapidly increasing every year in highly populated countries. Currently, only five drugs are available for obesity, but they have low efficacy and safety issues. This represents high medical unmet needs for a new drug which has higher efficacy and lower adverse effect than prevailing drugs. HTR2a is significantly associated with obesity. Lipogenesis in mature adipocytes was regulated through HTR2. In this poster presentation, discovery and biological evaluation of HTR2 antagonist will be presented
E-mail kmh0724@gist.ac.kr