|
Type |
Symposium |
Area |
Current Trends in Organic Chemistry II: Functional Organic Molecules |
Room No. |
Halla Hall B |
Time |
FRI 10:15-: |
Code |
ORGN2-4 |
Subject |
The Characteristics of Foldectures with Heteroatoms |
Authors |
Hee-Seung Lee Department of Chemistry, Korea Advanced Institute of Science and Technology, Korea |
Abstract |
Foldectures are a new class of crystalline peptidic material with unprecedented topological complexity derived from the rapid and non-equilibrium aqueous phase self-assembly of foldamers. We have opted to use trans-2-aminocyclopentanecarboxylic acid(ACPC) and/or 2-aminoisobutyric acid(Aib) as basic building blocks for initial exploration of the self-assembly. If the necessary functional groups were displayed on the specific facets of a well-defined structural framework with spatial periodicity, this “functionalized foldecture” would serve as a core material ready for further structural elaboration or could be employed as a huge protein-like catalyst. In this talk, our recent efforts in this research direction will be discussed. |
E-mail |
hee-seung_lee@kaist.ac.kr |