121st General Meeting of the KCS

Type Symposium
Area Current Trends in Organic Chemistry II: Functional Organic Molecules
Room No. Halla Hall B
Time FRI 10:15-:
Code ORGN2-4
Subject The Characteristics of Foldectures with Heteroatoms
Authors Hee-Seung Lee
Department of Chemistry, Korea Advanced Institute of Science and Technology, Korea
Abstract Foldectures are a new class of crystalline peptidic material with unprecedented topological complexity derived from the rapid and non-equilibrium aqueous phase self-assembly of foldamers. We have opted to use trans-2-aminocyclopentanecarboxylic acid(ACPC) and/or 2-aminoisobutyric acid(Aib) as basic building blocks for initial exploration of the self-assembly. If the necessary functional groups were displayed on the specific facets of a well-defined structural framework with spatial periodicity, this “functionalized foldecture” would serve as a core material ready for further structural elaboration or could be employed as a huge protein-like catalyst. In this talk, our recent efforts in this research direction will be discussed.
E-mail hee-seung_lee@kaist.ac.kr