121st General Meeting of the KCS

Type Oral Presentation
Area Oral Presentation of Young Analytical Chemists II
Room No. Room 201A
Time FRI 10:09-:
Code ANAL2.O-13
Subject Upconversion Nanoparticles Functionalized with Novel Amphiphilic Polymers for detection of drugs
Authors Seung Ha Lee, Salah Mahmoud Tawfik Ahmed, YONG-ILL LEE*
Department of Chemistry, Changwon National University, Korea
Abstract Upconversion nanoparticles (UCNPs) are a unique type of photoluminescence (PL) material in which lower energy excitation is converted into higher energy emission via multi-photon absorption processes. In this research, novel amphiphilic copolymers were synthesized to act as functionalizing agents for NaYF4:Yb3+/Er3+ UCNPs. The UCNPs coated with amphiphilic copolymers were characterized by using FTIR, SEM, UV, and PL instruments. These materials were used as optical sensors to detect various high blood pressure drugs including propranolol, metoprolol, atenolol, alprenolol, and carvedilol. Our developed sensors displayed good analytical performance such as low limits of detection and good linearith. Furthermore, the sensors have been applied successfully to determine the level of high blood pressure drugs in blood samples with good recoveries.
E-mail seungha0424@naver.com