122nd General Meeting of the KCS

Type Poster Presentation
Area Organic Chemistry
Room No. Grand Ballroom
Time 10월 18일 (목요일) 11:00~12:30
Code ORGN.P-63
Subject One-Pot Synthesis of 3-Substituted-2-Quinolone derivatives
Authors Byunghoon Ahn, Ill young Lee1, Hee Nam Lim1,*
Department of Chemistry, Korea University, Korea
1Eco-Friendly New Materials Research Center, Korea Research Institute of Chemical Technology, Korea
Abstract Herein, we describe a copper-mediated practical synthesis of 3-amido-2-quinolones in a one-pot reaction with 2-bromoarylaldehydes and malonamides. The morphologically distinct dendritic copper powder is discovered to promote condensation and the C-N bond formation. This method is complementary to conventional approaches using the Friedländer type reaction. It is economic due to use of inexpensive copper powder, and user friendly by easy setting.
E-mail qudgns3198@naver.com