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|
| Type |
Poster Presentation |
| Area |
Physical Chemistry |
| Room No. |
Grand Ballroom |
| Time |
10월 19일 (금요일) 11:00~12:30 |
| Code |
PHYS.P-209 |
| Subject |
Study of T1 relaxation properties of Polyacrylic acid (PAA) coating ultrasmall Gd2O3 nanoparticles for MRI |
| Authors |
Xu Miao, Gang Ho Lee*
Department of Chemistry, Kyungpook National University, Korea
|
| Abstract |
Magnetic resonance imaging contrast agents (MRI-CAs) distinguish normal and abnormal tissues inside the body through the differential contrast enhancement. For biomedical application MRI-CAs, nanoparticle should be highly water soluble, stable, non-toxic, and ultrasmall in particle size. In This work, we synthesized Gd2O3 nanoparticles coated by polyarylic acid (Mw =5100 Da) to obtain stable nano colloids, in order to achieve high-performance in vivo T1 MRI. The ligand PAA was directly coated on the nanoparticle surface. The colloidal suspension showed a high r1 value of 31.0 and r2/r1 ratio of 1.2 and exhibited high contrast T1 MR images. |
| E-mail |
kitty0927@live.cn |
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122nd General Meeting of the KCS