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|
| Type |
Poster Presentation |
| Area |
Analytical Chemistry |
| Room No. |
Grand Ballroom |
| Time |
10월 19일 (금요일) 11:00~12:30 |
| Code |
ANAL.P-343 |
| Subject |
Development of a multielement quantitation method from whole blood samples by ICP DRC MS |
| Authors |
Yujin Lee, Eunji Seo, Sangwon Cha*
Department of Chemistry, Hankuk University of Foreign Studies, Korea
|
| Abstract |
There are several attempts to assess all the environmental exposures of an individual and to reveal how the measured exposures affect to human health. Whole blood samples are one of the most widely used biomatrices for evaluating exposures due to their relatively easy accessibility. There have been many studies which tried to quantify elements from whole blood samples. Most of these studies focused on toxic heavy metals. For example, the US CDC laboratory manual published in 2014 described a method for quantitation of five toxic elements -cadmium, lead, manganese, mercury, and selenium- from whole blood samples. In this study, based on the US CDC laboratory manual, we tried to develop a multielement analysis method with whole blood samples that can cover up to about 15 elements including toxic heavy metals. To achieve this, we employed an efficient inductively coupled plasma (ICP) dynamic reaction cell (DRC) mass spectrometry (MS) platform with various cell gases. We also evaluated various sample preparation conditions and analysis parameters such as dilution factors, diluent compositions, cell gases, and cleaning procedures. In this presentation, we report the current progress in this development. |
| E-mail |
linu1017@gmail.com |
|
122nd General Meeting of the KCS