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|
| Type |
Symposium |
| Area |
Generation Networking Symposium in Analytical Chemistry |
| Room No. |
Room 321 |
| Time |
THU 16:20-: |
| Code |
ANAL1-3 |
| Subject |
Visualization of nanoparticle behavior in microchip and plant leaf using laser ablation ICP-MS |
| Authors |
Heung Bin Lim
Department of Chemistry, Dankook University, Korea |
| Abstract |
In our lab, ICP-MS immunoassay has been developed for the detection of biomarkers in serum, which recently expanded to viruses such as HIV-1 and HBsAg. Since multiplex detection became inevitable for clinical diagnosis, microchip sampling with laser ablation (LA) was studied in this work, for this, a microchip with 8x8 pillar-type islands, 300 μm in height and 250 μm in diameter was designed. First of all, behavior of metallic ions and nanoparticles as deposited on the island was visualized by LA-ICP-MS through imaging. Similarly, the behavior of SiO2 nanoparticles in plant leaf was also studied by a designed experimental model, which has been one of the difficulties in environmental analysis due to high background and strong interferences for 28Si+ ion. In addition, application of triple quadrupole ICP-MS to lower interfering ions and enhance sensitivity for the detection of SiO2 nanoparticles will be discussed in this presentation. |
| E-mail |
plasma@dankook.ac.kr |
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122nd General Meeting of the KCS