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| Type |
Poster Presentation |
| Area |
Analytical Chemistry |
| Room No. |
Grand Ballroom |
| Time |
10월 19일 (금요일) 11:00~12:30 |
| Code |
ANAL.P-350 |
| Subject |
An Analytical Method for Characterizing Naturally Occurring Compounds in Plants |
| Authors |
Su-Kyung Moon, Youjin Seo*
Analytical Research Center, Korea Institute of Toxicology, Korea
|
| Abstract |
Naturally sourced chemicals produced by plants represent a viable source for compounds targeting various diseases and are widely used in products such as cosmetics, vitamins, and drugs. Sourcing these compounds relies on both robust extraction methods and accurate, reliable, scientific assays evaluating their purity, effectiveness, and toxicity.
Herein, we report our assay aimed at measuring the compounds, chicoric acid and chrysophanol each derived from taraxacum officninale and cassis seed, respectively. Both these naturally occurring compounds have pivotal roles as antioxidants and are implicated in immunological disorders and atopic dermatitis.
We developed an analytical method using a HPLC-UV platform assessing system suitability, linearity, specificity, accuracy, precision, homogeneity and carry-over. Our method accurately measured both compounds. In addition, our results matched the acceptance requirement of validation criteria established by ICH. This method provides a means to adhere to established guidelines and to levels of naturally occurring compounds derived from plants.
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| E-mail |
moonsk@kitox.re.kr |
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122nd General Meeting of the KCS