122nd General Meeting of the KCS

Type Oral Presentation
Area Oral Presentation of Young Scholars in Electrochemistry
Room No. Room 320
Time THU 10:15-:
Code ELEC.O-6
Subject Electrochemical fabrication of gold nanoparticle/reduced graphene oxide hybrid nanocomposite modified electrodes for electrochemical biosensing applications
Authors Chang-Seuk Lee, Da Eun Oh1, Seungjoo Jang2, Tae Hyun Kim*
Department of Chemistry, Soonchunhyang University, Korea
1Chemistry, Soonchunhyang University, Korea
2chemistry, Soonchunhyang University, Korea
Abstract We introduce the preparation of the hybrid nanocomposite-modified electrode consisting of reduced graphene oxide (RGO) and gold nanoparticles (AuNPs) using the one-step electrochemical method. RGO/AuNPs nanocomposite was formed on a glassy carbon electrode by the co-reduction of GO and Au3+ using the potentiodynamic method. The RGO/AuNPs nanocomposite-modified electrode was produced by subjecting a mixed solution of GO and Au3+ to cyclic sweeping from -1.5 V to 0.8 V (vs. Ag/AgCl) at a scan rate 10 mV/s for 3 cycles. The modified electrode was characterized by scanning electron microscopy, Raman spectroscopy, contact angle measurement, electrochemical impedance spectroscopy, and cyclic voltammetry. The AuNP/rGO modified electrode was used as an electrochemical biosensor for the simultaneous and individual detection of dopamine (DA), ascorbic acid (AA), and uric acid (UA). The modified electrode shows high selectivity towards the determination of DA, AA, or UA in the presence of potentially active bioelements. The AuNP/rGO modified electrode was also functionalized with c-kemptide for protein kianase a (PKA) activity assay by electrochemical impedance spectroscopy. The PKA activity assay was successfully demonstrated utilizing the fabricated AuNP/rGO modified electrodes. Since this fabrication method utilizes only voltammetric scanning, it should be readily accessible for electrochemical biosensors for various applications.
E-mail eriklee0329@sch.ac.kr