122nd General Meeting of the KCS

Type Poster Presentation
Area Analytical Chemistry
Room No. Grand Ballroom
Time 10월 19일 (금요일) 11:00~12:30
Code ANAL.P-366
Subject Comparison of optical purity of 2,2,2-trifluoro-1-(9-anthryl)ethanol and some chiral compounds by NMR spectroscopy and high performance liquid chromatography
Authors Heo KyuSung, Gyuri Kim, Jeongjae Yu, Jae Jeong Ryoo1,*
Department of Chemistry, Kyungpook National University, Korea
1Department of Chemical Education, Kyungpook National University, Korea
Abstract

N-3,5-dinitrobenzoyl-(R)-phenylglycinol and its silylation product were used as an HPLC chiral stationary phase(CSP 1) for the resolution of racemic analytes including 2,2,2-trifluoro-1-(9-anthryl)ethanol(A).1 Due to the low selectivity(α=1.16) of A on CSP 1, determination of optical purity of A could not check correctly. In this study, we determined the optical purity of A and some chiral compounds using NMR spectroscopy and HPLC. Chiral selectors (Sel 1, Sel 2, Sel 3) used for NMR spectroscopy are shown below.

[1]. Jae Jeong Ryoo. et al. Chirality 28, 186–191 (2016)

E-mail kkuml@naver.com