122nd General Meeting of the KCS

Type Poster Presentation
Area Medicinal Chemistry
Room No. Grand Ballroom
Time 10월 18일 (목요일) 11:00~12:30
Code MEDI.P-305
Subject Pharmaceutical composition for the treatment of dry eye syndrome from Terminalia chebula
Authors Bong Geun Song, Pilju Choi1, Joonseong Hur2, Seon-Jun Choi, Young-Tae Park2, Jun Hyuk Choi3, Sang Il Jeon, Jungyeob Ham2,*
Department of Chemistry, Gangneung-Wonju National University, Korea
1Department of Oriental Medicine, Gachon University Global Campus, Korea
2Natural Products Research, Korea Institute of Science and Technology, Korea
3Chung-Ang University, Korea
Abstract Dry eye syndrome (DES) is an eye disease known as keratoconjunctivitis sicca, which causes defects in the eye and tear film due to various causes. Common symptoms include irritation, foreign body sensation, light sensitivity, and itching. Anti-inflammatory drugs such as corticosteroids and cyclosporine are also used as treatments for dry eye syndrome. However, there were risk of side effects such as glaucoma and cataract in long-term use. To solve the problems, we studied for the prevention and treatment of dry eye syndrome using natural products. In this presentation, we found that Terminalia chebula extracts or fractions play a crucial role in preventing or treating dry eye syndrome, and will show the therapeutic effect of dry eye syndrome through Terminalia chebula extract and fractions in In-vivo.
E-mail sod0617@hanmail.net