122nd General Meeting of the KCS

Type Symposium
Area Current Trends in Drug Repositioning
Room No. Room 306B
Time THU 17:10-:
Code MEDI-4
Subject Sharing Biologically-Relevant Compound Libraries and Bioassay Big-Data in Korea Chemical Bank
Authors Hyeon Kyu Lee
Korea Chemical Bank, Korea Research Institute of Chemical Technology, Korea
Abstract Korea Chemical Bank (KCB) has been established 18 years ago for the purpose of supporting new drug discovery and chemical biology researches by sharing biologically-relevant compound resources in Korea. KCB also aims to promote collaborative researches between provider and user of compounds by sharing the information of hit compounds and screening results. Currently, KCB has about a half-million of diverse small mw organic compounds and single-component natural products collected from Korea research groups and strategically purchased from international vendors. Every year, KCB has supported more than 100 projects for new drug discovery and chemical biology researches in Korea providing several hundreds of thousands compounds. Till now, KCB has supported more than 800 HTS campaigns and the accumulated number of compounds provided is more than 6 million since year 2000. Through the 18 years operation of KCB, KCB has accumulated over 5 million of biological activity screening data for the provided compound libraries against more than 800 disease targets. With the 5M screening data information, KCB has started a new project for the implementation of medicinal information big-data platform to help new drug discovery and chemical biology researches in Korea by sharing the analyzed and curated medicinal information big-data with Korean researches. In this talk, the current status of KCB chemical libraries, managing system and the implementation of KRICT medicinal information big-data platform will be introduced.
E-mail leehk@krict.re.kr