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| Type |
Poster Presentation |
| Area |
Electrochemistry |
| Room No. |
Grand Ballroom |
| Time |
10월 19일 (금요일) 11:00~12:30 |
| Code |
ELEC.P-504 |
| Subject |
Development of electrochemical biosensor for detection of human norovirus based on 2-dimensional material |
| Authors |
Seung Hoon Back, Tae Jung Park*, Kim Minwoo
Department of Chemistry, Chung-Ang University, Korea
|
| Abstract |
The harmfulness of norovirus, which can cause acute foodborne gastroenteritis, has increased worldwide because even at 102 copies/mL or fewer virus particles in the human body can trigger the disease. The primary reason for infection by this virus is closely related with the ingestion of contaminated shellfish, thus, highly sensitive and selective diagnosis tools are needed. Although there are many types of detection methods were considered in this study, the electrochemical biosensor was introduced for its sensitivity and reproducibility. Two-dimensional (2D) materials such as graphene or transitional dichalcogenides have attracted many researchers due to their superior properties on strength, stability, conductivity and biocompatibility. The thin film of MoS2 and WS2 are emerging electronic materials which show the high electrochemical properties. In this work, the development of WS2 nanomaterial morphology has been instituted by using hydrothermal method. Then, a cooperation of gold nanoparticles (AuNPs) on WS2 has been used for electrochemical detection of norovirus. The performance of the specific peptides has been studied with fluorescent optical assay, and gold-doped WS2-immobilized synthetic peptides have been studying cyclic voltammetry (CV) and impedance spectroscopy (EIS). These results demonstrated the potential of biosensor based on 2D materials in cooperation with AuNPs for the norovirus detection. The use of 2D materials promises the available in various of biosensing platform for point-of-care testing. |
| E-mail |
cutey1221@naver.com |
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122nd General Meeting of the KCS