|
|
| Type |
Poster Presentation |
| Area |
Medicinal Chemistry |
| Room No. |
Grand Ballroom |
| Time |
10월 18일 (목요일) 11:00~12:30 |
| Code |
MEDI.P-325 |
| Subject |
Mini-Review of biological applications of various free base and metallocorrole |
| Authors |
Sungrae Kim, Yonghwang Ha*
Department of Pharmaceutical Science, Jungwon University, Korea
|
| Abstract |
Recently corrole compounds, which have very similar core structure with porphyrin, have been attracted many interests with respect to synthetic strategies and biological applications. Although photophysical properties of corroles are similar porphyrin molecules, it has been known that biological characteristics exhibit more improved applicability for molecular imaging, detection and degradation of tumors, nucleic acid regulators, catalytic degradation of reactive oxygen/nitrogen species (ROS/RNS), anti-microorganism and generation of singlet oxygen as photosensitizers. Herein, we reviewed various free base- and metallo-corroles and their biological applications. |
| E-mail |
hyh3455@jwu.ac.kr |
|
122nd General Meeting of the KCS