As the need for sophisticated functional materials expands, expertise in synthetic organic chemistry has become more pivotal in developing new functional materials from the early designing-stage. In contrast to the traditional target-oriented organic synthesis which generally starts with a given target compound structure, function-driven organic synthesis should begin with understanding of the desired function of the materials to be synthesized. In depth understanding of the function as an organic chemist then enable him or her to design new molecules with optimal synthetic pathways. Over the last 16 years, our lab has been interested in developing new organic materials that exhibit interactions with three non-chemical stimuli; electricity, light, and heat. Electrochromic and conducting polymers are some of the examples for the electroactive organic materials studied in our lab.¹ Taking advantage of modern polymerization techniques such as controlled free radical polymerization (ATRP, NMRP, RAFT) and living ring opening metathesis polymerization (ROMP) along with wisely selected synthetic strategies, we could design and synthesize organic materials with finely tuned and desirable functionalities. Some examples include photocleavable block copolymer,² thermally activable ketene-generating polymers,³ MS tags for free radical initiated peptide sequencing (FRIPS),⁴ and matrix-free MS tags for laser desorption ionization (LDI).⁵ In this talk, a review of the research efforts made in our lab in these fields will be provided.
References
1. (a) Ko, H. C.; Kang, M.; Moon, B.; Lee, H. Adv. Mater. 2004, 16, 1712. (b) Ko, H. C.; Kim, S.; Lee, H.; Moon, B. Adv. Funct. Mater. 2005, 15, 905. (c) Park, Y. S.; Kim, D.; Lee, H.; Moon, B. Org. Lett. 2006, 8, 4699. (d) Heo, G.; Moon, B. Tetrahedron Lett. 2008, 49, 5540. (e) Kim, S.-H.; Shim, N.; Lee, H.; Moon, B. J. Mater. Chem. 2012, 22, 13558.
2. Kang, M.; Moon, B. Macromolecules 2009, 42, 455.
3. (a) Leibfarth, F.; Kang, M.; Ham, M.; Kim, J.; Campos, L. M.; Gupta, N.; Moon, B.; Hawker, C. J. Nature Chem. 2010, 2, 207. (b) Leibfarth, F. A.; Schneider, Y.; Lynd, N. A.; Schultz, A.; Moon, B.; Kramer, E. J.; Bazan, G. C.; Hawker, C. J. J. Am. Chem. Soc. 2010, 132, 14706.
4. (a) Lee, M.; Kang, M.; Moon, B.; Oh, H. B. Analyst 2009, 134, 1706. (b) Lee, J.; Park, H.; Kwon, H.; Kwon, H.; Jeon, A.; Kim, H. I.; Sung, B.; Moon, B.; Oh, H. B. Anal. Chem. 2013, 85, 7044.
5. Kang, N.; Lee, J.-M.; Jeon, A.; Oh, H. B.; Moon, B. Tetrahedron 2016, 72, 5612.