|
Type |
Oral Presentation |
Area |
Oral Presentation of Young Analytical Chemists II |
Room No. |
Room 321 |
Time |
FRI 10:20-: |
Code |
ANAL2.O-13 |
Subject |
Comparative Analysis of Lectin based Glycoproteomics and Triglyceride and Glucose (TyG) Index between Elderly Yoga Groups
|
Authors |
Miseon Jeong, Jinwook Lee1, Wonryeon Cho* Department of Bio-nanochemistry, Wonkwang University, Korea 1Bio-nanochemistry, Wonkwang University, Korea |
Abstract |
We had already investigated the efficacy of elderly yoga by identifying and comparing the glycoproteins in human plasma. This study focused on comparing the efficacy of yoga with the change of Triglyceride and Glucose (TyG) Index from Advanced level group and Beginner level group. The TyG Index can predict diabetes with simple calculation. The glycoproteins from the yoga participants’ plasma are affinity selected using self-packed Lycopersicon esculentum lectin (LEL) columns. After that, peptides from affinity selected proteins were deglycosylated with PNGase F and identified with nLC-MS/MS. The results show that the number of plasma glycoproteins in Advanced level group is less than that in Beginner’s group, demonstrating an inverse correlation between number of plasma glycoproteins and yoga experience. Additionally, the decrease of TyG Index in Advanced level group is higher than Beginner level group, which is similar to the tendency of glycoprotein change between elderly healthy yoga groups. |
E-mail |
misun9422@wku.ac.kr |
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