122nd General Meeting of the KCS

Type Oral Presentation
Area Oral Presentation of Young Analytical Chemists II
Room No. Room 321
Time FRI 10:20-:
Code ANAL2.O-13
Subject Comparative Analysis of Lectin based Glycoproteomics and Triglyceride and Glucose (TyG) Index between Elderly Yoga Groups
Authors Miseon Jeong, Jinwook Lee1, Wonryeon Cho*
Department of Bio-nanochemistry, Wonkwang University, Korea
1Bio-nanochemistry, Wonkwang University, Korea
Abstract We had already investigated the efficacy of elderly yoga by identifying and comparing the glycoproteins in human plasma. This study focused on comparing the efficacy of yoga with the change of Triglyceride and Glucose (TyG) Index from Advanced level group and Beginner level group. The TyG Index can predict diabetes with simple calculation. The glycoproteins from the yoga participants’ plasma are affinity selected using self-packed Lycopersicon esculentum lectin (LEL) columns. After that, peptides from affinity selected proteins were deglycosylated with PNGase F and identified with nLC-MS/MS. The results show that the number of plasma glycoproteins in Advanced level group is less than that in Beginner’s group, demonstrating an inverse correlation between number of plasma glycoproteins and yoga experience. Additionally, the decrease of TyG Index in Advanced level group is higher than Beginner level group, which is similar to the tendency of glycoprotein change between elderly healthy yoga groups.
E-mail misun9422@wku.ac.kr