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|
| Type |
Poster Presentation |
| Area |
Life Chemistry |
| Room No. |
Exhibition Hall 2 |
| Time |
4월 19일 (금요일) 11:00~12:30 |
| Code |
LIFE.P-338 |
| Subject |
3D imaging of cancer cell mitosis with upconversion nanoparticles |
| Authors |
Seonjong Kim, Kang Taek Lee1,*
Depertment of Chemistry, Gwangju Institute of Science and Technology, Korea
1Division of Physical Chemistry Department of Chemi, Gwangju Institute of Science and Technology, Korea
|
| Abstract |
In chemical therapy of cancer, cell mitosis continues to occur. In case the drugs are the ones that require uptake into the cells, the concentration of the drugs per cell is forced to reduce due to the subsequent and continual mitosis. In order to image such division in real time and analyze the statistics involved in the drug partitioning we used 3D live cell imaging with upconversion nanoparticles (UCNPs). As a result, negatively charged functionalized UCNP is more significantly divided to mother and daughter cells. |
| E-mail |
mikube@gist.ac.kr |
|
123rd General Meeting of the KCS