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| Type |
Poster Presentation |
| Area |
Organic Chemistry |
| Room No. |
Exhibition Hall 2 |
| Time |
4월 18일 (목요일) 11:00~12:30 |
| Code |
ORGN.P-147 |
| Subject |
Asymmetric Synthesis of cis-5-Aminomethyl-3-(4-methoxyphenyl)-dihydrofuran-2(3H)-one |
| Authors |
Sonhwan Kim, Won Koo Lee1,*, Hyun-Joon Ha2,*
Chemistry, Hankuk University of Foreign Studies, Korea
1Department of Chemistry, Sogang University, Korea
2Department of Chemistry, Hankuk University of Foreign Studies, Korea
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| Abstract |
The asymmetric synthesis of (2R,5S)-5-aminomethyl-3-(4-methoxyphenyl)dihydrofuran-2(3H)-one as ths most potent selective inactivator of monoamine B was successfully achieved by applying a newly developed synthetic method toward -aminomethyl--lactone from intramolecular aziridine-ring opening in 63% overall yield from commercial starting material. |
| E-mail |
sonwhan123@naver.com |
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123rd General Meeting of the KCS