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|
| Type |
Poster Presentation |
| Area |
Organic Chemistry |
| Room No. |
Exhibition Hall 2 |
| Time |
4월 18일 (목요일) 11:00~12:30 |
| Code |
ORGN.P-148 |
| Subject |
Metal-Free Aza-Claisen Type Ring Expansion of Vinyl Aziridines: An Expeditious Synthesis of Seven Membered N-Heterocycles |
| Authors |
Deepak Singh, Hyun-Joon Ha1,*
Chemistry, Hankuk University of Foreign Studies, Korea
1Department of Chemistry, Hankuk University of Foreign Studies, Korea
|
| Abstract |
A metal free, Lewis acid catalyzed approach for the intermolecular [5+2] cycloadditon of vinyl aziridines with alkynes has been reported for the synthesis of highly functionalized seven membered N-heterocycles. The method has broad substrate scope and applicable for both terminal and internal alkynes as well as vinyl aziridines under mild reaction conditions which delivers a variety of structurally different azepines ring systems in high yield up to 92%. |
| E-mail |
deepakmsu@gmail.com |
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123rd General Meeting of the KCS