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|
| Type |
Symposium |
| Area |
Advanced Instrumental Analysis Chemistry for Protein Dynamics Studies |
| Room No. |
Room 202 |
| Time |
THU 16:30-06:55 |
| Code |
ANAL1-3 |
| Subject |
Correlative Super-Resolution Microscopy |
| Authors |
Doory Kim
Department of Chemistry, Hanyang University, Korea |
| Abstract |
The rise of super-resolution microscopy (SRM, Research field of the Nobel Prize in Chemistry 2014, Technologies to watch in 2019 by Nature) over the past decade has drastically improved the resolution of light microscopy to ∼10 nm, thus creating exciting new opportunities and challenges for correlative microscopy. Correlative microscopy, the integration of two or more microscopy techniques performed on the same sample, produces results that emphasize the strengths of each technique while offsetting their individual weaknesses. The new opportunities afforded by correlative SRM have hence motivated extensive new research, providing multidimensional, multi-scale, and corroborated information about a system regarding morphology, functionality, dynamics, cellular context, and chemical composition. In this presentation, I will talk about our technology development and recent applications of correlative SRM and other microscopy techniques, including electron microscopy, live-cell imaging, and spectroscopy. Using this approach, we studied filamentous influenza viruses, the purine biosynthetic enzymes organization complex called purinosomes, and the ring-opening reaction of photochromism molecules. |
| E-mail |
dooldoory@gmail.com |
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123rd General Meeting of the KCS