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| Type |
Poster Presentation |
| Area |
Organic Chemistry |
| Room No. |
Exhibition Hall 2 |
| Time |
4월 18일 (목요일) 11:00~12:30 |
| Code |
ORGN.P-186 |
| Subject |
Visible-light-promoted synthesis of biaryl compounds |
| Authors |
Boseok Hong, Anna Lee*
Department of Chemistry, Myongji University, Korea
|
| Abstract |
Biarenes are a commonly found moiety in various natural products, bioactive compounds, and synthetic intermediates. Because of their structural importance, development of novel and more efficient synthetic methods have received significant attention from the organic communities over decades. The most common strategy to access the biaryl scaffold is the well-known transition metal catalyzed aryl-aryl coupling reactions such as Suzuki, Negishi, Ullmann, Stille, and Kumada coupling etc. These synthetic methods have provided powerful tools for synthesizing biaryl compounds, but they still have limitations like using toxic,expensive reagents and/or reacting under harsh conditions. Therefore, the development of more mild and efficient strategies would be greatly valuable for the construction of Aryl-Aryl bonds. Here in, we report visible-light-mediated aryl-aryl coupling reaction that does not need any metal catalysts or photosensitizer. This novel and environmentally benign method provides an alternative route to established synthetic approaches to afford the desired products from easily available substrates in high yields. |
| E-mail |
bshong77@naver.com |
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123rd General Meeting of the KCS