123rd General Meeting of the KCS

Type Symposium
Area Recent Trends in Supramolecular Chemistry
Room No. Room 305+306
Time FRI 15:40-16:00
Code INOR3-3
Subject Self-assembly of BODIPY based Metal Supramolecules: Synthesis and Applications
Authors Chang Yeon Lee
Department of Energy and Chemical Engineering, Incheon National University, Korea
Abstract Coordination-driven self-assembly process remains one of the most convenient technique to design complicated yet interesting large metal based supramolecules with well-defined architectures.1 The size, shape, geometry and overall properties can be fine-tuned by proper selection of appropriate electron-deficient metal-nodes and electron-donor multidentate ligands. Since the initial findings on palladium and platinum macrocycles in the early 1990s by Fujita et. al., Stang and Cao, macrocycles based on other metal centers have attracted substantial interest in different important fields of chemistry.2 Following a similar strategy, Therrien et. al. synthesized ruthenium-based rectangles, prisms, and cubes with excellent biological properties.3 My research group in Incheon National University, introduced the use of highly fluorescent pyridyl-BODIPY (boron-dipyrromethene) ligands to develop novel metal-based supramolecules.4 In this talk, I will present the recent progress of metal-based BODIPY supramolecules evolved from our research group and their applications in cancer therapy.5 References: (1) T. R. Cook, Y.-R. Zheng, P. J. Stang, Chem. Rev. 2013, 113, 734-777. (2) (a) M. Fujita, J. Yazaki, K. Ogura, J. Am. Chem. Soc. 1990, 112, 5645-5647; (b) P. J. Stang, D. H. Cao, J. Am. Chem. Soc. 1994, 116, 4981-4982. (3) B. Therrien, CrystEngComm. 2015, 17, 484-491. (4) C. Y. Lee, O. K. Farha, B. J. Hong, A. A. Sarjeant, S. T. Nguyen, J. T. Hupp, J. Am. Chem. Soc. 2011, 133, 15858-15861. (5) (a) G. Gupta, A. Das, N. B. Ghate, T. Kim, J. Y. Ryu, J. Lee, N. Mandal, C. Y. Lee, Chem. Commun. 2016, 52, 4274-4277; (b) G. Gupta, A. Das, S. Panja, J. Y. Ryu, J. Lee, N. Mandal, C. Y. Lee, Chem. Eur. J. 2017, 23, 17199-17203; (c) G. Gupta, A. Das, K. C. Park, A. Tron, H. Kim, J. Mun, N. Mandal, K.-W. Chi, C. Y. Lee, Inorg. Chem. 2017, 56, 4615-4621.
E-mail cylee@inu.ac.kr