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| Type |
Poster Presentation |
| Area |
Analytical Chemistry |
| Room No. |
Exhibition Hall 2 |
| Time |
4월 19일 (금요일) 11:00~12:30 |
| Code |
ANAL.P-281 |
| Subject |
Optimization of sample preparation methods for the multi-class chemical analysis of the deciduous teeth |
| Authors |
Jun young Park, Sangwon Cha1,*
Chemistry, Hankuk University of Foreign Studies, Korea
1Department of Chemistry, Hankuk University of Foreign Studies, Korea
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| Abstract |
Exposomics, a research field that tries to measure all the exposures of an individual and reveal how the measured exposures relate to health, receives an increasing attention. Recently, deciduous teeth have been proposed to be retrospective temporal biomarkers for exposomics researches due to its specific structure and growth pattern. However, sample preparation and analysis steps for the tooth matrix have not been explored extensively and need to be standardized. In this study, we evaluated various sample preparation procedures for extracting small organic chemicals from tooth samples and tried to develop a fast and reliable LC-MS/MS method for quantifying multi-class exposure chemicals. With the optimized sample preparation and analysis protocol, various environmental exposure chemicals such as phthalates, phenols, and paraben were quantitatively measured from the deciduous tooth samples. |
| E-mail |
pjy931119@naver.com |
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123rd General Meeting of the KCS