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| Type |
Poster Presentation |
| Area |
Polymer Chemistry |
| Room No. |
Exhibition Hall 2 |
| Time |
4월 19일 (금요일) 11:00~12:30 |
| Code |
POLY.P-33 |
| Subject |
Compartmentalized Bimetal Nanostructures for Photonics-based Bio-sensing |
| Authors |
Eun Young Hwang, Dong Woo Lim1,*
Bionano Technology, Hanyang University, Korea
1Department of Bionano Engineering, Hanyang University, Korea
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| Abstract |
Compartmentalized bimetal nanostructures have distinct surface properties as well as unique plasmonic properties at each metallic compartment, as compared to those of the single metallic counterparts. Especially, surface-enhanced Raman scattering (SERS) has been of great importance for biochemical detection because it has ultra-high sensitivity, narrow bandwidth as well as significant multiplexing capabilities. Herein, we report synthesis of core-shell, eccentric- and heterodimeric bimetal nanostructures with anisotropy via competitive ligand coordination between two immiscible ligands at different molar ratios. Both hydrophobic- and hydrophilic ligands were competitively bound to Au seeds asymmetrically, and Ag ions were simultaneously reduced, forming into the second Ag metallic compartment onto the Au seeds. A diblock copolymer as a ligand was synthesized via reversible addition-fragmentation chain transfer polymerization, and catechol groups were chemically conjugated with its hydrophilic block. In addition, to prove that these bimetal nanostructures could serve as SERS nanoprobes for biosensing applications, we demonstrated the formation of sandwich-type immunocomplexes composed of SERS nanoprobes and magnetic beads in the presence of target proteins, and showed SERS-based quantitative analysis. Conclusively, this work has great potential as multi-functional nanostructures for SERS-based biosensing. |
| E-mail |
sinh553@hanyang.ac.kr |
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123rd General Meeting of the KCS