|
Type |
Poster Presentation |
Area |
Life Chemistry |
Room No. |
Exhibition Hall 2 |
Time |
4월 19일 (금요일) 11:00~12:30 |
Code |
LIFE.P-378 |
Subject |
Synthesis of all cases of caffeoylquinic acid via protected quinic acid |
Authors |
Jinwoo Seo, Sang Jeon Chung1,*, Hyeyeon Jun2 Department of Pharmacy, Sungkyunkwan University, Korea 1College of Pharmacy, SungKyunKwan University, Korea 2Sungkyunkwan University, Korea |
Abstract |
Caffeoylquinic acids (CQAs) was reported that have various biological activities including antioxidant, antibacterial, anticancer, and others. (-)- Quinic acid has four hydroxyl group and selective hydroxyl group protection in poly hydroxyl molecules continues to be a challenge in synthetic chemistry. In this study, a total 15 compounds were synthesized that combine one caffeic acid, two caffeic acid, three caffeic acid and four caffeic acid in (-)-quinic acid by selectively protecting the hydroxyl group. Furthermore, the compounds that I synthesized will treat specific cells to find out any other biological activity and which hydroxyl group is active. |
E-mail |
jinwooseo0409@gmail.com |
|