123rd General Meeting of the KCS

Type Poster Presentation
Area Life Chemistry
Room No. Exhibition Hall 2
Time 4월 19일 (금요일) 11:00~12:30
Code LIFE.P-378
Subject Synthesis of all cases of caffeoylquinic acid via protected quinic acid
Authors Jinwoo Seo, Sang Jeon Chung1,*, Hyeyeon Jun2
Department of Pharmacy, Sungkyunkwan University, Korea
1College of Pharmacy, SungKyunKwan University, Korea
2Sungkyunkwan University, Korea
Abstract Caffeoylquinic acids (CQAs) was reported that have various biological activities including antioxidant, antibacterial, anticancer, and others. (-)- Quinic acid has four hydroxyl group and selective hydroxyl group protection in poly hydroxyl molecules continues to be a challenge in synthetic chemistry. In this study, a total 15 compounds were synthesized that combine one caffeic acid, two caffeic acid, three caffeic acid and four caffeic acid in (-)-quinic acid by selectively protecting the hydroxyl group. Furthermore, the compounds that I synthesized will treat specific cells to find out any other biological activity and which hydroxyl group is active.
E-mail jinwooseo0409@gmail.com