123rd General Meeting of the KCS

Type Poster Presentation
Area Electrochemistry
Room No. Exhibition Hall 2
Time 4월 18일 (목요일) 11:00~12:30
Code ELEC.P-466
Subject Rapid determination of norovirus using electrochemical nanobiosensor via WS2 nanoflower-bioreceptor hybrid
Authors Seung Hoon Back, ChanYeong Park1, Tae Jung Park*
Department of Chemistry, Chung-Ang University, Korea
1Chung-Ang University, Korea
Abstract Norovirus is one of the infectious diseases in the world by eating raw foods which were infected by others, and there are many people could be infected to touch and to eat contaminated things easily. Thus, it is important to develop highly sensitive and selective diagnosis tools of detection for norovirus are needed. So far, there are myriad types of detection methods were studied for the virus, among them, we have focused on the electrochemical nanobio hybrid sensor for its sensitive and selective properties. In this work, we have studied nanomaterials and to develop their morphology. Extending to the 2D flat structure and 3D structure of flower-like shape materials (WS2NFs) enhances their properties as a bio sensing platform due to their spacious surface area. In addition, the WS2NFs were coated with AuNPs on their surface to improve the electrochemical properties and to provide the immobilization place with the peptides. The performance of the nanobio hybrid electrochemical sensor was tested by electrochemical impedance spectroscopy, and to result to a low detection limit (3.79 copies/mL) in real virus sample by extracted from an oyster. These results indicate that the nanobio hybrid sensor can be applied to various biosensing platforms for point-of-care testing. Moreover, the potential of biosensor based on 2D materials in cooperation with AuNPs for the norovirus detection was demonstrated by the experiment results.
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