123rd General Meeting of the KCS

Type Oral Presentation
Area Oral Presentation of Young Analytical Chemists I
Room No. Room 202
Time THU 10:28-10:32
Code ANAL1.O-23
Subject Development of Novel Upconversion Nanoparticles Functionalized with Amphiphilic Polymers for detection of Alprenolol
Authors Seung Ha Lee, Salah Mahmoud Tawfik Ahmed, Yong-ill Lee*
Department of Chemistry, Changwon National University, Korea
Abstract Upconversion nanoparticles (UCNPs) are a unique type of photoluminescence(PL) material in which lower energy excitation is converted into higher-energy emission via multi-photon absorption processes. In this research, novel amphiphilic copolymers were synthesized to act as functionalizing agents for NaLuGdF4:Yb3+/Er3+ UCNPs. The UCNPs coated with amphiphilic copolymers were characterized by using FTIR, 1HNMR, SEM, TEM, UV, and PL instruments. These materials were used as optical sensors to detect Alprenolol which is kind of high blood pressure treatment. Our developed sensors displayed good analytical performance such as low limits of detection and good linearity. Furthermore, the sensors were applied to determine the level of high blood pressure drugs in human urine and serum samples with good recoveries. Keywords: Upconversion nanoparticles, amphiphilic copolymers, optical sensors, alprenolol, human serum samples, human urine samples
E-mail seungha0424@naver.com