KCS

We have developed a benzene-based tripodal 2-aminooxazoline receptor system for selectivity and affinity recognition of ammonium, potassium, sodium and alkylammonium ions. The benzene-based tripodal 2-aminooxazoline was prepared readily from the benzene-based tripodal N-(2-hydroxyethyl)-N'-phenyl thioureas with p-toluenesulfonyl chloride and sodium hydroxide in one pot reaction. affording the required O-alkylation products in good yield under mild reaction condition We evaluated association constants of guest molecules with tripodal 2-aminooxazoline receptors by the picrate extraction method. Benzene-based tripodal 2-aminooxazoline are found to be  promising receptors for the selective recognition of NH₄⁺ over K⁺ with binding affinities. We will be discussed the binding affinity and selectivity between the 2-aminooxazoline receptor and another ions.