We present a novel fully integrated centrifugal microfluidic device, “Lab-on-a-disc”, for various kinds of applications in analytical chemistry. In biomedical applications, a bead-based enzyme-linked immune-sorbent assay was fully integrated on a disc starting from whole blood for the analysis of multiple protein biomarkers for cardiovascular diseases . The detection sensitivity could be enhanced significantly by using electrochemical detection on a spinning disc and employing nanomaterials such as electrospun nanofibers . In molecular diagnostics, pathogen specific DNA could be extracted from whole blood on a disc within 12 minutes  and for the food safety application, a further research fully integrated all the process for Salmonella detection from the milk within 30 minutes by using an isothermal DNA amplification method, Recombinase Polymerase Amplification. Lab-on-a-disc was also employed to automate solid phase extraction of caffeine from real beverages such as a coffee or a soft drink for the quantitative analysis of caffeine concentration . The “Lab-on-a-disc” technology is advantageous because of the capability to integrate and automate all the process into a disc-shaped device with simple, size-reduced, and cost-efficient instrumentation. Integration with microfluidic technology allows more precise control of fluids while also reducing the reagent consumption, the required analysis time and handling errors. We believe these approaches will not only improve the performance of the target analysis but also potentially have great impact on global healthcare.
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