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  • 09월 05일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제120회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Developed to Overhauser Dynamic Nuclear Polarization Nuclear Magnetic Resonance Systems for Signal Enhancement

2017년 8월 31일 11시 20분 14초
ANAL2.O-36 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
금 10시 : 31분
Analytical Chemistry - Oral Presentation of Young Analytical Chemists II
저자 및
JiWon Kim, Seung-Bo Saun1, Oc Hee Han1,*
Department of Chemistry and Nano Science, Ewha Womans University, Korea
1Western Seoul Center, Korea Basic Science Institute, Korea
Nuclear magnetic resonance (NMR) spectroscopy has advantages such as non-destructive observation of molecular structure and dynamics, analysis of amorphous samples, and high selectivity of nuclear species to be observed. However, NMR has the disadvantage of low sensitivity because it uses low energy. In order to overcome the disadvantage of NMR, overhauser dynamic nuclear polarization (ODNP) NMR system which amplifies NMR signals from several tens to several hundred times using the interaction of electron spins and nuclear spins within about 1 nm from the electron spin centers. Therefore, a local region can be designated by selectively positioning the spin markers in the sample. ODNP NMR can be used to measure the diffusion rate of water in a variety of materials and to measure the dependence of binding between protein and water on solvents. In our laboratory, an Electron Paramagnetic Resonance (EPR) spectrometer and NMR components (radio frequency pulse modules, NMR tuning boxes, ODNP NMR probes, etc.) has been assembled together and instrumental optimization for the best amplification is currently in progress.