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제122회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Comparative Analysis of Lectin based Glycoproteomics and Triglyceride and Glucose (TyG) Index between Elderly Yoga Groups

2018년 8월 22일 16시 55분 11초
ANAL2.O-13 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
금 10시 : 20분
Analytical Chemistry - Oral Presentation of Young Analytical Chemists II
저자 및
Miseon Jeong, Jinwook Lee1, Wonryeon Cho*
Department of Bio-nanochemistry, Wonkwang University, Korea
1Bio-nanochemistry, Wonkwang University, Korea
We had already investigated the efficacy of elderly yoga by identifying and comparing the glycoproteins in human plasma. This study focused on comparing the efficacy of yoga with the change of Triglyceride and Glucose (TyG) Index from Advanced level group and Beginner level group. The TyG Index can predict diabetes with simple calculation. The glycoproteins from the yoga participants’ plasma are affinity selected using self-packed Lycopersicon esculentum lectin (LEL) columns. After that, peptides from affinity selected proteins were deglycosylated with PNGase F and identified with nLC-MS/MS. The results show that the number of plasma glycoproteins in Advanced level group is less than that in Beginner’s group, demonstrating an inverse correlation between number of plasma glycoproteins and yoga experience. Additionally, the decrease of TyG Index in Advanced level group is higher than Beginner level group, which is similar to the tendency of glycoprotein change between elderly healthy yoga groups.