KCS

The development of environment-friendly and sustainable catalysts has attracted a great attention from academia and industry. Since late 1990s, organocatalysts were exploited due to its non-toxic character. The phosphoric acids and secondary amine catalysts initiated and more and more organic molecule-based catalysts were developed. Compared to transition-metal catalysts, the organocatalyst system was suffered by its low efficiency and limited applications utilizing highly reactive intermediates. In this presentation, I will share the development of new strong Brønsted acids, imidodiphosphoramides (IDPi) and their applications, which overcome long-standing limitations. The new organocatalysts enabled various challenging reactions which cannot be achieved with conventional organo- and transition-metal catalysts especially in enantioselective reactions.