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학술발표회초록보기

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  • 08월 18일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제108회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Monitoring of corticosteroids in cosmetic products made in Korea

등록일
2011년 8월 1일 12시 54분 42초
접수번호
1028
발표코드
Ⅳ-ANAL.P-182 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
금 <발표Ⅳ>
발표형식
포스터
발표분야
분석화학
저자 및
공동저자
남윤식, 이기수, 박현미, 이연희, 이강봉
한국과학기술연구원 특성분석센터, Korea
Some cosmetic products manufactured in Korea have been suspected to contain anti-inflammatory corticosteroids without indication on the label of cosmetic products. Cosmetic product samples (number of samples = 65) of manufacturers charged by consumers have been collected in local and online markets of Korea. They were analyzed by LC-MS/MS. LC-MS/MS was used to confirm corticosteroids in cosmetic samples with diagnostic ions (m/z). Linearity was studied with 0.1~10 μg/mL range in all corticosteroids. Good correlation coefficients (r2? 0.997) were found and their limits of quantitation were 4.68~7.97 ng/g at each corticosteroids. At three different concentrations spanning the linear dynamic ranges, mean recoveries were 97.2~113.5% and precisions (RSD) for intra-day and inter-day analysis were less than 8.9%. Also, accuracy (Bias %) were less than 11.8%. The results showed that the 0.76~0.94 μg/g levels of prednisolone were detected in four cosmetic products and triamcinolone acetonide in samples was monitored with the concentration of the range of 11.5~272 μg/g in nine samples.

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