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학술발표회초록보기

초록문의 abstract@kcsnet.or.kr

결제문의 member@kcsnet.or.kr

현재 가능한 작업은 아래와 같습니다.
  • 08월 18일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제108회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Encoded Microparticles and Partipetting for High Throughput Material Chemistry

등록일
2011년 8월 1일 22시 56분 24초
접수번호
1399
발표코드
MAT1-8 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
목 17시 : 10분
발표형식
심포지엄
발표분야
재료화학 - Microfluidic-Based Materials Chemistry
저자 및
공동저자
권성훈, 정수은1, 이승훈1, 송영훈1, 김지윤1
서울대학교 전기공학부, Korea
1서울대학교 전기컴퓨터공학부, Korea

In drug discovery, the process of identifying drug target requires screening hundreds of thousands of drug libraries, which is like searching for a needle in a haystack. To deliver each chemical or biological compound to the assay system, a quantitative liquid handling technique is essential in high-throughput manner. Encoded particles have a demonstrated value for multiplexed high-throughput bioassays such as drug discovery and clinical diagnostics. In diverse samples, the ability to use a large number of distinct identification codes on assay particles is important to increase throughput. Proper handling schemes are also needed to readout these codes on free-floating probe microparticles. Herein, the pivotal point in drug screening process is how to handle million different chemicals in a simple and fast way. In this talk, we present a bioassay platform for high-throughput drug screening based on encoded drug-laden microparticles via a single step, using a method named as ‘partipetting’. Partipetting is defined as a method of delivering encoded drug-laden microparticles to chemically isolated reaction wells via fluidic self-assembly. The partipetting enables parallel handling of millions of different drugs making heterogeneous bioassay platform at once, thus greatly reduces the repetition of drug introduction into the microwell platform. 


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