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학술발표회초록보기

초록문의 abstract@kcsnet.or.kr

결제문의 member@kcsnet.or.kr

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  • 03월 02일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제109회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Fluorescent labeled nanoparticles enable to detect the stem-cell-derived hepatocytes

등록일
2012년 2월 23일 16시 22분 31초
접수번호
1474
발표코드
BIO.P-703 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
4월 25일 (수요일) 18:00~21:00
발표형식
포스터
발표분야
생명화학
저자 및
공동저자
신진섭
한양대학교 생명공학과, Korea
Hepatic cirrhosis characterized by permanent scarring which restricts its own function and makes it difficult to get cured. Stem cell transplantation is emerging as a possible new treatment for liver cirrhosis, and recent animal studies have documented benefits of stem cell therapy for hepatic fibrosis model. However, the underlying mechanism of stem cell therapy is still unclear. Among the proposed mechanism, the cell replacement mechanism is the oldest and most important one ? permanently damaged tissue can be replaced by normal ones to restore a function. In the present study, c5.5 labeled superparamagnetic iron oxide (SPIO) were used to label human mesenchymal stem cells. Uptaken fluoresce labeled nanoparticle enables to detect and monitor the transplanted stem cells, therefore we can confirm the direct incorporation and differentiation into hepatocyte-like cells of transplanted stem cell.

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