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학술발표회초록보기

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  • 03월 02일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제109회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Development of Uricase-CdTe nanoparticles for optical sensing of uric acid

등록일
2012년 2월 23일 16시 27분 57초
접수번호
1478
발표코드
ANAL.P-641 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
4월 25일 (수요일) 18:00~21:00
발표형식
포스터
발표분야
분석화학
저자 및
공동저자
서민호, B.T.Huy, 임재민, 이용일
창원대학교 화학과, Korea
Simple and controllable synthetic procedure for CdTe nanoparticles was developed directly in the aqueous phase. TheCdTe nanoparticles are advantageous as the emission can be tuned by changing reaction time and pH values. The interaction between CdTe nanoparticles and hydrogen peroxide was investigated by using fluorescence spectroscopy. Effect of different stabilizers has been studied. The results showed that the fluorescence quenching effect demonstrated excellent sensitivity to H2O2. The convenient optical detection methodology of uric acid was developed based on the fluorescence quenching of CdTe nanoparticles by H2O2 which was produced from the enzymatic reaction of uricase.The detection conditions, reaction time, the concentration of uricase were optimized. The results show that CdTe nanoparticles can be potentially used as a fluorescence probe for detecting uric acid. This optical analysis method could provide a new feasible, simple, and generic way to analyze numerous H2O2-dependent enzymes due to many enzymatic reactions can produce hydrogen peroxide.

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