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학술발표회초록보기

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  • 03월 02일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제109회 대한화학회 학술발표회, 총회 및 기기전시회 안내 a fluorescent nitric oxide(NO) sensor with Rh-complex in silica beads

등록일
2012년 2월 29일 18시 47분 07초
접수번호
1535
발표코드
MAT.P-1211 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
4월 25일 (수요일) 18:00~21:00
발표형식
포스터
발표분야
재료화학
저자 및
공동저자
양난희, 구은회1
고려대학교 바이오마이크로시스템, Korea
1한국세라믹기술원 바이오IT융합, Korea
Nitric oxide (NO) has been interested in chemistry and biology since it was identified as the endothelium-derived relaxation factor. In addition, NO was established a ubiquitous messenger molecule in the cardiovascular, nervous and immune systems and tumor progression. However NO is highly reactive and it can be converted to other species quickly, thus it is very difficult to detect and monitor the concentration of NO in vivo. SO many methodologies of detecting NO have been developed include electrochemical, EPR, chemiluminescent, and fluorescence signaling. Our method in developing sensors that utilize the formation of transition-metal complex to trigger a change in fluorescence is based on a strategy that takes advantage of the well-known fluorescence-quenching properties of transition metal complexes with partially filled d-shells. Furthermore our nanohybrids incorporated system can sense NO reversibly by turn-on emission and display more effectively than solution environment.

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