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제114회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Extremely stable nanoemulsions fabricated by interfacial assembly of amphiphilic block copolymers at oil-water interfaces

2014년 8월 28일 13시 58분 59초
POLY.P-46 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
10월 15일 (수요일) 16:00~19:00
저자 및
신경희, 박한희1, 김진웅1,*
한양대학교 바이오나노공학과, Korea
1한양대학교 응용화학과, Korea
Recently, there have been intense interests in fabrication of stable nanoemulsions by incorporation of amphiphilic block copolymers. These block copolymers have abilities not only to reduce the interfacial tension at the oil-water interface, but also to form a mechanically flexible but tough polymer film at the interface. These unique behaviors make them truly useful as polymeric surfactants. The objective of this study is to demonstrate that extremely stable nanoemulsions can be produced by effective assembly of amphiphilic block copolymers during phase inversion from a water-in-oil emulsion to an oil-in-water emulsion. The phase inversion emulsification process is established by characterizing the emulsion phase properties as well as by confirming remarkably improved emulsion stability. We also conduct the feasibility tests for a variety of oils, including natural oils, hydrocarbon oils, and synthetic oils. Finally, we show experimentally that the nanoemulsions fabricated in this study remarkably improve transdermal delivery, which would explore practical applications in dermatology and cosmetics. Acknowledgement: This study was supported by a grant of the Korea Healthcare Technology R&D Project, Ministry of Health & Welfare, Republic of Korea (Grant No.: A103017)