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제114회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Water Soluble Ultrasmall Mixed Gadolinium Dysprosium Oxide Nanoparticles for MRI Contrasting Agent

등록일
2014년 8월 28일 14시 31분 36초
접수번호
0992
발표코드
PHYS.P-421 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
10월 15일 (수요일) 16:00~19:00
발표형식
포스터
발표분야
물리화학
저자 및
공동저자
tirusew tegafaw, 이강호1,*
경북대학교 화학과, Ethiopia
1경북대학교 화학과, Korea
Surface coated magnetic nanoparticles have been very intensively investigated so far due to their potential applications to a variety of biological and biomedical areas. In this work we synthesized ultra small water soluble GdDy mixed oxide nanoparticles with biofunctinalized surface coating. D-glucuronic acid was used for the surface coating of the nanoparticles. The water soluble and biocompatible D-Glucuronic acid coated GdDy mixed oxide nanoparticles have drawn tremendous attraction in the application of magnetic resonance imaging. The structural, morphological and magnetic properties of these synthesized products were characterized by using X-ray diffraction (XRD), high-resolution transmission electron microscopy (HRTEM), Fourier transform infrared spectroscopy (FTIR), TGA, and SQUID magnetometer. To confirm the validity of mixed gadolinium dysprosium oxide nanoparticles for T1, T2 dual MRI imaging ,we performed in vitro and in vivo imaging and relaxivity measurements.

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