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  • 09월 01일 18시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제118회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Identification of antioxidants and tyrosinase inhibitors from Lespedeza cuneate G. Don using off-line and ultrafiltration combined with HPLC

등록일
2016년 9월 1일 16시 23분 49초
접수번호
2420
발표코드
MEDI.P-510 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
10월 13일 (목요일) 11:00~12:30
발표형식
포스터
발표분야
의약화학
저자 및
공동저자
지준*, 임순성1
에프에이 부설연구소, Korea
1한림대학교 식품영양학과, Korea
Lespedeza cuneate G. Don is one of plant species of leguminosae family widely distributed in eastern and southern Asia. It is used as traditional asian medicine for treatment of the diseases of the liver, kidneys and lungs. A previous study has reported thatL. cuneate extract showed excellent antioxidant capacity and tyrosinase inhibitory activity. However, there is no research reports the antioxidants and tyrosinase inhibitors existed in L. cuneate even though its chemical constituents have been well analyzed. In the present study, The L. cuneate was extracted by 70% ethanol. In order to rapidly identify the antioxidants and tyrosinase inhibitors from L. cuneate, the off-line ABTS-HPLC assay and ultrafiltration-HPLC assay were performed. In results, vitexin, kaemferol, astragalin, and quercetin were identified as antioxidants, and vitexin was identified as the tyrosinase inhibitor from L. cuneate. These results suggest that the extract of L. cuneate has the potential use as antioxidants and skin whitening agent, and off-line ABTS-HPLC and ultrafiltration-HPLC could be useful for high-throughput identification of antioxidants and tyrosinase inhibitors in natural products.

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