abs

학술발표회초록보기

초록문의 abstract@kcsnet.or.kr

결제문의 member@kcsnet.or.kr

현재 가능한 작업은 아래와 같습니다.
  • 09월 01일 18시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제118회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Surface Analysis by Mass Spectrometry for Nano-Bio Applications

등록일
2016년 9월 8일 13시 48분 33초
접수번호
2524
발표코드
PHYS1-1 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
목 13시 : 00분
발표형식
분과기념
발표분야
물리화학 - Machine Learning and Chemistry
저자 및
공동저자
이태걸
한국표준과학연구원(KRISS) 미래융합기술부, Korea
Although the collisional cascade process in ToF-SIMS is unable to produce secondary ions with a molecular weight of over m/z 2,000 without the use of noble metals or special matrixes, time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging is a powerful technique for producing chemical images of small biomolecules (ex. metabolites, lipids, peptides) “as received” because of its high molecular specificity, high surface sensitivity, and submicron spatial resolution. For large biomolecules, matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) has been used for molecular identification of proteins in the discovery of disease-related biomarkers as a key platform technique in proteomics.
For this talk, I will show that the label-free ToF-SIMS imaging technique can be a platform technology for characterization of organic-conjugated nanoparticles, disease diagnosis and drug screening. In addition, I will discuss the potential capability of Ar-cluster SIMS to study omics, particularly proteomics and lipidomics for brain studies.

상단으로