초록문의 abstract@kcsnet.or.kr

결제문의 member@kcsnet.or.kr

현재 가능한 작업은 아래와 같습니다.
  • 03월 08일 23시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제127회 대한화학회 학술발표회 및 총회 Electrochemical biosensors using a photoredox catalyst and a nanozyme

2021년 2월 16일 19시 37분 45초
ELEC1-4 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
목 14시 : 35분
Electrochemistry - New Horizons for Molecular Electrochemistry and Its Applications
저자 및
Haesik Yang
Department of Chemistry, Pusan National University, Korea
Two electrochemical biosensors using new catalytic reactions will be presented. In the first part, washing-free DNA detection using surface-plasmonic-field-induced photoredox catalysis will be introduced. A distance-dependent surface plasmonic field induces rapid photoredox catalysis of surface-bound catalytic labels, and distance-dependent mediated electron transfer allows for rapid electron transfer from the surface-bound labels to the electrode. An optimal system consists of a chemically reversible acceptor (Ru(NH3)63+), a chemically reversible photoredox catalyst (eosin Y), and a chemically irreversible donor (triethanolamine). In the second part, a sensitive immunosensor using a metal nanozyme with ester hydrolysis activity will be introduced. Metal nanoparticle surfaces are used for peroxidase- and oxidase-like nanozymes but not for esterase‐like nanozymes. It is found that metal nanoparticle surfaces rapidly catalyze non-redox ester hydrolysis in the presence of redox H3N−BH3 (AB). Metal hydrides are readily generated on a Pt nanoparticle (PtNP) from AB, and as a result the PtNP becomes electron-rich, which might assist nucleophilic attack of H2O on the carbonyl group of an ester. The nanozyme system based on PtNP, AB, and 4-aminonaphthalene-1-yl acetate provides an electrochemical signal-to-background ratio much higher than natural enzymes, due to the rapid ester hydrolysis and redox cycling involving the hydrolysis product.