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  • 02월 22일 16시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

The antioxidative activities of Callicarpa japonica Thunb on LPS-induced cytokine protection in murine macrophages cell line RAW 264.7

등록일
2008년 2월 12일 14시 02분 17초
접수번호
0974
발표코드
30P210포 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
목 <발표Ⅰ>
발표형식
포스터
발표분야
분석화학
저자 및
공동저자
정은주, 신장철, 서지원, 김일광
원광대학교 생명나노화학부,
The antioxidant activities and anti-inflammatory effects of Callicarpa japonica Thunb was investigated. Callicarpa japonica Thunb were extracted with 70% methanol and fractionated with H2O, n-hexane, chloroform, ethyl acetate and BuOH to get active fractions. The antioxidant properties of the fractions were determined by several detecting methods ; free radical scavenging test (1,1-diphenyl-2-picryl- hydrazy l; DPPH), reductive potentials method and total phenolics assay. The ethyl acetate fraction of Callicarpa japonica Thunb showed strong effects for reductive potential, free radical scaverging, and total phenolics assay at tested concentrations. The active fraction showed anti-inflammatory effects by cytotoxic activity test(MTT) and nitric oxide(NO) assay. The active fraction suppressed nitric oxide(NO) generation in mouse macrophags Raw 264.7 cell stimulated by lipopolysaccharide.

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