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  • 02월 22일 16시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

The effect of nano material on mice. Micro/Nano silica particle diet

등록일
2008년 2월 13일 13시 27분 05초
접수번호
1103
발표코드
29P46포 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
금 <발표Ⅴ>
발표형식
포스터
발표분야
물리화학
저자 및
공동저자
장익순, 소수정1, 한종수1
한국기초과학지원연구원 광주센터,
1전남대학교 화학과,
The size dependent effect of silica particle on mice was studied by contacting intestinal tract. The silica was obtained from rice husk and treated to particles with nano (~30 nm) and micron (~30 μm). The mice, Balb/c (20~30g) and C57BL/6J for the experiment were classified to normal, nano sized silica (1 %), and micron sized silica (1 %) dieted groups. After feeding for 10 weeks, the blood was tested biochemically and hematologically. There was no difference in the tested items except ALT(Alanine Aminotransferase). The value of ALT increased in the nano particle dieted group. H&E staining of the liver of the nano particle dieted group showed some fatty liver pattern while the contents of Si in the livers of the groups were almost the same. From the results, it was suggested that the nano sized silica showed a negative effect on the liver even though there was no significant different on the health.

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