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  • 02월 22일 16시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

Use of Peptide for Selective and Sensitive Detection of Anthrax Biomarker using Square Wave Voltammetry

등록일
2008년 2월 14일 11시 12분 27초
접수번호
1293
발표코드
30P237포 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
목 <발표Ⅰ>
발표형식
포스터
발표분야
분석화학
저자 및
공동저자
Tran Ngoc Huan
한양대학교 화학과,
A short peptide composed of 16 amino acids rather than an antibody has been utilized to selectively detect Anthrax biomarker by using square wave voltammetry. A peptide of high affinity to PA was immobilized on the surface of gold electrode and allowed to bind PA selectively. The determination was based on the reduction peak at 730 mV for PA captured by a peptide against Ag/AgCl reference electrode; while, the reduction peak of PA itself on the gold surface was located at 680 mV. Using the proposed scheme, PA concentration up to 20 pM could be detected. The result present that a short peptide could replace the role of antibody, that has been widely used to selectively recognize a target biomarker in the field of electrochemical biosensor. Future study will be directed to evaluate the reproducibility as well as selectivity, which are required to address for practical applications

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