abs

학술발표회초록보기

초록문의 abstract@kcsnet.or.kr

결제문의 member@kcsnet.or.kr

현재 가능한 작업은 아래와 같습니다.
  • 02월 22일 16시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

Aminolyses of 2,4- Dinitrophenyl and 3,4-Dinitrophenyl 2-thiophenecarboxylates: Effect of ortho-Substituent on Reactivity and Mechanism

등록일
2008년 2월 14일 13시 32분 05초
접수번호
1382
발표코드
32P240포 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
금 <발표Ⅴ>
발표형식
포스터
발표분야
유기화학
저자 및
공동저자
서진아, 엄익환1
이화여자대학교 나노과학부 화학과,
1이화여자대학교 나노과학부,
Second-order rate constants (kN) have been measured spectrophotometrically for reactions of 3,4-phenyl 2-thiophenecarboxylates (2) with a series of secondary alicyclic amines in 20 mol % DMSO at 25.0oC. The Brønsted-type plot exhibits a downward curvature for the aminolysis of 2, which is similar to that reported for the corresponding reactions of 2,4-phenyl 2-thiophenecarboxylates (1). Substrate 2 is less reactive than 1 but the reactivity difference becomes smaller as the amine basicity increases. Dissection of the second-order rate constants into the microscopic rate constants has revealed that the reaction of 2 results in a smaller k2/k–1 ratio but larger k1 value than that of 1. Steric hindrance has been suggested to be responsible for the smaller k1 value found for the reactions of 1, since the ortho-substituent of 1 would inhibit the attack of amines.

상단으로